--Access to real-world medical data is often restricted due to privacy regulations, posing a significant barrier to the advancement of healthcare research. Synthetic data offers a promising alternative; however, generating realistic, clinically valid, and privacy-conscious records remains a major challenge. Recent advancements in Large Language Models (LLMs) offer new opportunities for structured data generation; however, existing approaches frequently lack systematic prompting strategies and comprehensive, multi-dimensional evaluation frameworks. In this paper, we present SynLLM, a modular framework for generating high-quality synthetic medical tabular data using 20 state-of-the-art open-source LLMs, including LLaMA, Mistral, and GPT variants, guided by structured prompts. We propose four distinct prompt types, ranging from example-driven to rule-based constraints, that encode schema, metadata, and domain knowledge to control generation without model fine-tuning. Our framework features a comprehensive evaluation pipeline that rigorously assesses generated data across statistical fidelity, clinical consistency, and privacy preservation. We evaluate SynLLM across three public medical datasets, including Diabetes, Cirrhosis, and Stroke, using 20 open-source LLMs. Our results show that prompt engineering significantly impacts data quality and privacy risk, with rule-based prompts achieving the best privacy-quality balance. SynLLM establishes that, when guided by well-designed prompts and evaluated with robust, multi-metric criteria, LLMs can generate synthetic medical data that is both clinically plausible and privacy-aware, paving the way for safer and more effective data sharing in healthcare research. Access to real-world medical data is frequently restricted due to privacy regulations, ethical constraints, and institutional barriers, posing a significant challenge for the development of AI-driven healthcare solutions. While data protection laws such as the Health Insurance Portability and Accountability Act (HIP AA) [11] and the General Data Protection Regulation (GDPR) [37] are essential for safeguarding patient confidentiality, they often hinder the availability of data for clinical model development and research.

Large language models (LLMs) have become integral to our professional workflows and daily lives. Nevertheless, these machine companions of ours have a critical flaw: the huge amount of data which endows them with vast and diverse knowledge, also exposes them to the inevitable toxicity and bias. While most LLMs incorporate defense mechanisms to prevent the generation of harmful content, these safeguards can be easily bypassed with minimal prompt engineering. In this paper, we introduce the new Thoroughly Engineered Toxicity (TET) dataset, comprising manually crafted prompts designed to nullify the protective layers of such models. Through extensive evaluations, we demonstrate the pivotal role of TET in providing a rigorous benchmark for evaluation of toxicity awareness in several popular LLMs: it highlights the toxicity in the LLMs that might remain hidden when using normal prompts, thus revealing subtler issues in their behavior.

This paper explores SynTOD, a new synthetic data generation approach for developing end-to-end Task-Oriented Dialogue (TOD) Systems capable of handling complex tasks such as intent classification, slot filling, conversational question-answering, and retrieval-augmented response generation, without relying on crowdsourcing or real-world data. SynTOD utilizes a state transition graph to define the desired behavior of a TOD system and generates diverse, structured conversations through random walks and response simulation using large language models (LLMs). In our experiments, using graph-guided response simulations leads to significant improvements in intent classification, slot filling and response relevance compared to naive single-prompt simulated conversations. We also investigate the end-to-end TOD effectiveness of different base and instruction-tuned LLMs, with and without the constructed synthetic conversations. Finally, we explore how various LLMs can evaluate responses in a TOD system and how well they are correlated with human judgments. Our findings pave the path towards quick development and evaluation of domain-specific TOD systems. We release our datasets, models, and code for research purposes.

The proliferation of large language models (LLMs) has sparked widespread and general interest due to their strong language generation capabilities, offering great potential for both industry and research. While previous research delved into the security and privacy issues of LLMs, the extent to which these models can exhibit adversarial behavior remains largely unexplored. Addressing this gap, we investigate whether common publicly available LLMs have inherent capabilities to perturb text samples to fool safety measures, so-called adversarial examples resp.~attacks. More specifically, we investigate whether LLMs are inherently able to craft adversarial examples out of benign samples to fool existing safe rails. Our experiments, which focus on hate speech detection, reveal that LLMs succeed in finding adversarial perturbations, effectively undermining hate speech detection systems. Our findings carry significant implications for (semi-)autonomous systems relying on LLMs, highlighting potential challenges in their interaction with existing systems and safety measures.